Package: CITMIC
Type: Package
Title: Estimation of Cell Infiltration Based on Cell Crosstalk
Version: 0.1.3
Maintainer: Junwei Han <hanjunwei1981@163.com>
Authors@R: c(person(given = "Junwei", family = "Han", email = "hanjunwei1981@163.com", role  = c("aut", "cre", "cph")),
             person(given = "Xilong", family = "Zhao", role  = "aut")
             )
Description: A systematic biology tool was developed to identify cell infiltration via Individualized Cell-Cell interaction network. 'CITMIC' first constructed a weighted cell interaction network through integrating Cell-target interaction information, molecular function data from Gene Ontology (GO) database and gene transcriptomic data in specific sample, and then, it used a network propagation algorithm on the network to identify cell infiltration for the sample. Ultimately, cell infiltration in the patient dataset was obtained by normalizing the centrality scores of the cells.
License: GPL (>= 2)
Encoding: UTF-8
LazyData: true
Depends: R (>= 2.10)
Imports: fastmatch, igraph, parallel, stats
RoxygenNote: 7.3.2
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2025-10-11 02:44:25 UTC; 89800
Author: Junwei Han [aut, cre, cph],
  Xilong Zhao [aut]
Repository: CRAN
Date/Publication: 2025-10-15 10:40:07 UTC
Built: R 4.7.0; ; 2026-05-07 02:58:11 UTC; windows
